Stanford|Synthetic Biology
Stanford|Synthetic Biology
Enabling flourishing futures in partnership with life
Enabling flourishing futures in partnership with life
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What is synthetic biology?
What is synthetic biology?
Synthetic Biology (SB) is fundamental science and engineering research that advances building with biology. From creating cellular therapies that detect and treat disease, harnessing organisms that eat carbon out of the air to transform pollution into stuff we use every day, and building microbes that live with plants to produce their own fertilizer, synthetic biology holds promise to allow us to rethink how we meet human needs on a planetary scale in a way that is accessible, distributed, and fair.
The Stanford Synthetic Biology community enables interdisciplinary activities, supporting an ecosystem of research and learning. Our holistic approach encompasses diverse areas of work, each exploring fundamental questions and possibilities with the ultimate desire of addressing societal needs.
All together now!
All together now!
Stewart Brand, Stanford Class of 1960 (Biology), wrote,
"I propose six significant levels of pace and size in the working structure of a robust and adaptable civilization. [...] In a healthy society each level is allowed to operate at its own pace, safely sustained by the slower levels below and kept invigorated by the livelier levels above." (Long Now)
With pace-layer thinking in mind we are exploring and advancing synthetic biology (SB) among and across all aspects of civilization, inclusive of but not limited to biotechnology and bioeconomy. We also note that intrinsic to pace layers thinking is a bias towards the human, a concept we suspect may evolve along with SB. Thus, we have adopted a coupled-rings visual metaphor, in place of layers, for now.
Stanford SB News
Stanford SB News
On Art &, the StanfordArts podcast, Drew Endy and Phil Ross explore art, synthetic biology, fungi, and materials, as well as discuss how artists and scientists can work side-by-side to prototype more ethical, regenerative, and connected futures.
June 2025
Qi Lab developed a CRISPR technology that delivers RNA to damaged neurons and stimulates regrowth – paving the way for potential treatments targeting neurodegenerative diseases like ALS and spinal muscular atrophy.
May 2025
Build-a-Cell workshop hosted on Stanford's campus. Build-a-Cell is a global network of researchers that aims to develop synthetic living cells.
May 2025
Stanford hosted the 2nd Synthetic Biology for Sustainability Symposium on May 7 bringing together over 200 people to discuss how synthetic biology can power a more sustainable future.
May 2025
Gao Lab introduces revolutionary new protein and RNA editing platforms for cell-based therapy.
March 2025
Stanford BioE PhD student Bella Archibald named Top 30 Young Scientists working on breakthrough solutions to climate change, through the Inflection Award.
March 2025
Hoover Bio-Strategies and Leadership (BSL) hosts the Organization for Economic Cooperation and Development (OECD) for a one-day workshop on biotechnology policy.
February 2025
Trained on DNA of all known living species – Evo 2 can predict the form and function of proteins in the DNA of all domains of life and run experiments in a fraction of the time it would take a traditional lab. This was co-led by Brian Hie's lab.
February 2025
Combing through scads of DNA, chemical structure, and functional data, Mike Jewett & his team have created an AI-guided platform that helps design, build, and test powerful new enzymes.
January 2025
Callie Chappell & collaborators propose a national plan for LABraries, where the public can learn and explore biology and biotechnology.
January 2025
Mirror Life? As researchers discuss the idea of building organisms from molecules with reversed structures, a new report from a group of 38 scientists argues it’s not worth the risk.
December 2024
Possu Huang's lab reports on de novo TRACeR platform for targeting MHC-I and MHC-II antigens.
December 2024
Michael Fischbach and his team engineered a skin bacterium into a topical vaccine that protected mice against tetanus. This breakthrough could revolutionize vaccination by providing a needle-free alternative.
December 2024
The Stanford Synthetic Biology for Sustainability grant program is seeking proposals that aim to use synthetic biology to make life on Earth more sustainable, broadly defined.
Deadline: January 31, 2025
Alice Ting & her team develop a new antigen-activated synthetic receptor tool called PAGER that enhances control of cellular activity.
December 2024
Brian Hie and collaborators at the Arc Institute have developed Evo, the first large-scale machine learning model trained on DNA.
November 2024
From Petri Dish to Palette: an art exhibition showcasing the vibrant potential of synthetic biology in the arts, on display from November 7–18.
November 2024
Stanford 2024 iGEM team earns gold at the iGEM Grand Jamboree, the annual global synthetic biology competition.
November 2024
Hoover’s Bio-Strategies & Leadership (BSL) team welcomed 20 senior congressional staff for a two-day intensive bootcamp on emerging biotechnologies.
October 2024
Jenn Brophy and Helen Dang awarded 2024-25 Burt McMurtry Arts Initiatives Fund grant through the Office of the Vice President at the Arts to launch a Synthetic Biology x Arts workshop to teach others how to cultivate biopigments using bacteria.
October 2024
Stanford Synthetic Biology Community kicked off the 2024-25 school year with a vibrant Fall Welcome event, bringing together students, faculty, and researchers.
September 2024
Congrats to the five teams awarded Synthetic Neuroscience Grants to advance tools for studying brain circuits. $1.24M was awarded by Wu Tsai Neurosciences, Stanford ChEM-H, and Bio-X.
September 2024
Read how Professors Rogelio Hernandez-Lopez, Hawa Racine Thiam, Drew Endy, Michael Jewett, and Kyle Daniels are engineering cells for new purposes
August 2024
Stanley Qi & Mike Jewett's lab members creates $2 CRISPRkits, bringing affordable gene-editing experiments to high schools.
August 2024
On Global Health: Smallpox Biosecurity in a New Era of Technology
June 2024
Stanford bioengineers host Secretary of State Anthony Blinken for a roundtable discussion on synthetic biology.
May 2024
Professor Sang Yup Lee of KAIST joins us for the inaugural Stanford Frontiers in Synthetic Biology Distinguished Lecture to discuss metabolic engineering for sustainability and health
May 2024
Chris Voigt joins the Synthesis community to discuss tracking engineered microbiomes from space and over decades
Hosted by Stanford BioE Department Colloquium
May 2024
Christina Smolke joined the Sustainability Accelerator for an enlightening discussion on the profound impact of synthetic biology on pharmaceutical biomanufacturing and global sustainability.
April 2024
Jay Daniels, Founding Scientist at Moonlight Bio, shares insights on his journey from academia to industry at SB.Talk.
April 2024
The Wu Tsai Neurosciences Institute, Sarafan Chem-H, and Bio-X seek proposals for the inaugural Synthetic Neuroscience Grant Program to spark new collaborations between neuroscience and synthetic biology researchers across Stanford University.
February 2024
Stanford Emerging Technology Review launch at the Hoover office in Washington, DC.
January 2024
The second Synthetic Neuroscience Forum was held with talks from Michael Lin and Xiaojing Gao. Hosted by Sarafan ChEM-H, Bio-X, Wu Tsai Neurosciences Institute.
January 2024
Building Biology student symposium brought in guest speakers: Patrick Hsu (UCB), Katie Galloway (MIT), Magdalena Zernika-Goetz (Caltech), Neil Shubin (UChicago)
Hosted by Stanford Genetics and Developmental Biology Training Program
January 2024
The Hoover Institution and Stanford School of Engineering have launched the inaugural edition of the Stanford Emerging Technology Review, which aims to help policymakers understand a range of fast-developing new technologies, from AI and cryptography to robotics and synthetic biology.
December 2023
The first Synthetic Neuroscience Forum was held with Drew Endy and Sergiu Pasca, leading a discussion on the opportunities of synthetic biology in neuroscience. Hosted by Sarafan ChEM-H, Bio-X, Wu Tsai Neurosciences Institute.
December 2023
Stanford Bioengineering Department launches "Engineering Life for Planet Health" faculty search and seeking candidates who align with the department's vision of rapidly advancing large-scale solutions to address critical planetary challenges.
November 2023
Qi Lab develops an ultrasound method for precise control in gene regulation and base editing - both in cells and living animals.
October 2023
Congratulations to Xiaojing Gao, Steven Banik, and Stanley Qi for being awarded NIH High Risk, High Reward program grants for their work in synthetic biology.
October 2023
Mike Jewett kicks off the new school year by facilitating a community discussion at SB.Talk on synthetic biology for sustainability.
September 2023
Stanford 2023 iGEM team designed and developed Phil's Laberia, an educational video game where students can learn bioengineering wet lab skills.
August 2023
Fischbach Lab provides new insights into how T cells respond to commensal microbes.
August 2023
Qi Lab develops a CRISPR/Cas9 approach to edit dendritic cells for wound healing
August 2023
Bintu Lab works on high-throughput functional characterization of combinations of transcriptional activators and repressors
August 2023
Endy Lab publishes a paper on engineering tRNA abundances for synthetic cellular systems
Learn from Jenn Brophy and Drew Endy's EdEquityLab x Stanford's Intro to Bioengineering course. Now available online!
July 2023
SB.Talk sparks discussion around synthetic biology at Stanford. Join the conversation in the Shriram Tea Room every other Tuesday 12pm.
July 2023
Jewett Lab developed a cell-free method to rapidly discover and characterize functional antibodies in under 24 hours.
July 2023
Qi Lab reports on 'CLIP' (CRISPR for long-fragment integration via pseudovirus) method for stable expression of large transgenes via the knock-in of an integrate-deficient lentivirus.
May 2023
Prof. Alice Ting has been elected to the National Academy of Sciences. Ting is a Professor of Genetics, of Biology and, by courtesy, of Chemistry.
May 2023
The inaugural Synthetic Biology for Sustainability Symposium had over 200 attendees representing across schools of Medicine, Engineering, Sustainability, and H&S.
May 2023
Synthetic Biology for Sustainability Symposium will take place on May 1.
Hosted by the Deans of the School of Medicine, the School of Engineering, and the Stanford Doerr School of Sustainability, this symposium will focus on how we might tackle some of the biggest challenges in sustainability using some of the newest innovations in synthetic biology.
Fischbach Lab engineered a common skin bacterium, S. epidermidis to produce a tumor antigen. When applied to mice, it resulted in a potent immune response against a distant tumor.
April 2023
Bintu Lab leads efforts towards large-scale mapping and mutagenesis of human transcriptional effector domains
April 2023
Stanford Synthetic Biology meets for the first community event of 2023
March 2023
Sattely Lab discovered 22 enzymes for biosynthesis of limonoids in Citrus and Melia.
January 2023
Prof. Mike Jewett joins Stanford Bioengineering as their newest faculty member.
January 2023
Gao Lab develops new tool -- programmable RNA sensing using ADAR editing in living cells.
October 2022
Biden Administration issued an Executive Order on Advancing Biotechnology and Biomanufacturing Innovation for a Sustainable, Safe, and Secure American Bioeconomy.
September 2022
Does synthetic biology offer anything new? Watch the non-technical conversation with Drew Endy about advancements in synthetic biology and related economic and governance opportunities with the Hoover Institution.
August 2022
Sergiu Pasca explains how to reverse engineer the human brain by growing organoids.
August 2022
Dr. Alice Cheng of Fischbach Lab & colleagues make human microbiome from scatch.
September 2022
The Bintu lab takes a synthetic approach to understand and program chromatin-mediated gene silencing & activation.
June 2022
Brophy et al. pioneer synthetic genetic circuits in plant roots.
August 2022
Townshend, Kaplan, & Smolke report over 200 new RNA biosensors to potential drug molecules.
July 2022
Endy & McKelvey reflect on synthetic biology's potential impacts for democracy and national security, hosted by Los Alamos National Lab. and moderated in part by Stanford's Prof. Hank Greely.
July 2022
Preparing for and preventing future pandemics. Two new grants provide key resources
June 2022
"What is synthetic biology and what is its potential? These stories explain." Megan Palmer's WEF Council partners with Faber Futures to explore and elaborate on inclusive futures.
June 2022
"Building a Bottom-Up Bioeconomy," Stanford's Dr. Megan Palmer and colleagues make the case by reimagining industrialization.
May 2022
Making With Mushrooms! 17 years later the second-ever issue of Adventures in Synthetic Biology begins to emerge.
May 2022
"Mother Nature, Bioweapons, & Lab Accidents: Guarding Against the Next Global Biological Catastrophe," Stanford's Freeman Spogli's CISAC welcomes Dr. Jaime Yassif of NTI. March 2022
Prof. Pasca explores how to understand the mysteries of the human mind by growing neural circuits from scratch.
Jan 2022
Prof. Skylar-Scott & team explain what must be made real to ultimately print working hearts from scratch.
March 2022
"Who wouldn't want to ride on a Wooly Mammoth?," Stanford undergraduates explore dystopian and utopian futures that might arise via resurrecting extinct species. March 2022
Prof. Ting's team pioneers LuCID, a genetically-encoded tool for realtime measurement of calcium dynamics in live cells, including neurons and immune cells.
March 2022
Prof. Steinmetz and colleagues pioneer synthetic genomics for understanding the fundamental rules of genome architecture.
March 2022
The New Yorker explores if what biology needs right now is more synthesis. Prof. Zia chimes in.
February 2022
Prof. Brophy & Dinneny pioneer living Boolean logic in plants for climate resilience.
February 2022
Gao lab pioneers the engineering of protein circuits that let cells talk to each other.
February 2022
Novozymes recognizes Adjunct Prof. Smolke & team with 100,000 DKK prize for sustainable medicines.
February 2022
How can American strengthen its bioeconomy? Adjunct Prof. Palmer and colleagues chart the path.
February 2022
Can we engineer crops to withstand climate change? Prof. Brophy makes the case.
January 2022
NY Times explores what's happening and might be possible via synthetic biology. E.g., it's personal!
November 2021
Megan Palmer, co-chair of World Economic Forum Council on Synthetic Biology, and team release report on synthetic biology.
April 2021
Danielle Mai's group discusses the role of synthetic biology in a class of protein-based materials.
September 2021
Stanley Qi's team develops CRISPR-Cas13 resource for targeting RNA viruses.
March 2021
Prashanth in the Smolke lab pioneers brewing of tropane alkaloids from scratch.
September 2020
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